Cancer Pharmacology: A Comprehensive Guide to Anticancer Drugs and Therapies

Authored by renowned experts Ashkan Emadi MD PhD and Judith E. Karp MD, Cancer Pharmacology: An Illustrated Manual of Anticancer Drugs, Second Edition is a visually stunning reference that delves into the fundamental basic and clinical science of all approved, effective, and life-prolonging drug therapies in oncology. This extensively revised edition focuses on clinical context, application, and management, providing a practical, bench-to-bedside approach for both early-career and seasoned clinicians.

A Practical and Patient-Oriented Guide

The book offers in-depth coverage of major advances in cancer pharmacology, encompassing the latest standards of care for solid tumors and hematologic malignancies. It explores a wide range of anticancer agents, including traditional cytotoxic agents, targeted genomic, epigenomic, hormonal, and immunotherapeutic agents, as well as a new chapter on pharmacogenomics.

With over 150 elegant illustrations, each chapter meticulously details the tumor microenvironment, chemical structures of agents, pharmacodynamics, pharmacokinetics, pharmacogenomic and molecular properties, and mechanisms of action. This comprehensive guide covers alkylating agents, antimetabolites, antimitotics, epigenetic modulators, hormonal agents, targeted therapies, monoclonal antibodies, immunotherapeutic agents, and more.

Updated to Reflect the Latest Advances in Cancer Research

This second edition has been thoroughly updated to include new FDA-approved treatments and applications, ensuring that readers stay abreast of the latest developments in the field. Written by leading experts in cancer pharmacology, this book is an essential resource for anyone involved in the basic, translational, or clinical aspects of oncology and hematology, including clinicians, pharmacists, nurses, and trainees.

Key Features

• Over 150 beautiful illustrations to facilitate understanding of complex concepts
• More than 160 high-yield hematology and oncology board-style chapter review questions with descriptive rationales
• Comprehensive explanations of how chemotherapy, targeted therapy, immunotherapy, and hormonal therapy work, and why they are expected to be effective in various treatment modalities
• In-depth discussions on challenges related to drug development, drug approval, and regulatory issues in relation to anticancer treatments
• Important pharmacotherapy context with clinical pearls in each chapter to support a patient-oriented, bedside approach

Published by Demos Medical, this second edition is available in paperback format, featuring 454 pages of comprehensive content. The ISBN-10 is 0826149324, and the ISBN-13 is 978-0826149329.