Toxicity and Toxicodynamics: A Comprehensive Guide to Pharmatoxicology in Drug Research

Authored by Rakesh Kumar Tekade, this insightful volume is the first in the Essentials of Pharmatoxicology in Drug Research series, providing a thorough overview of toxicology, risk assessment, and mechanisms crucial to pharmaceutical product development.

Understanding Cellular Responses to Chemical Toxicants

The book delves into the various types of cellular responses to chemical toxicants, shedding light on the mechanisms of drug toxicity and their relevance to the development of pharmaceutical products.

Mechanistic and Predictive Toxicology: Leveraging Omics and Computer-Aided Technologies

The volume explores the application of omics and computer-aided technologies in mechanistic and predictive toxicology, enabling researchers to better understand and predict the toxicological effects of drugs.

Toxicity Studies: State-of-the-Art Testing and Dose Selection

The book covers the latest advancements in toxicity studies, including state-of-the-art testing methods for evaluating detrimental pathways and optimal dose selection strategies.

The Role of Regulatory Agencies in Toxicity Studies

The volume also examines the critical role played by regulatory agencies in ensuring the safety and efficacy of pharmaceutical products through rigorous toxicity studies.

Clinical Interventions for Acute Poisoning: Pharmacotherapy and Managed Care Strategies

In addition, the book discusses clinical interventions for acute poisoning, including pharmacotherapy and managed care strategies, providing valuable insights for healthcare professionals and researchers alike.

This comprehensive resource is an essential read for anyone seeking to deepen their understanding of the drug development process and stay abreast of the latest concepts and advancements in toxicology research.

Key Features:

• Examines toxicological risk assessment in drug research
• Discusses toxicity mechanisms and their relevance to pharmaceutical product development
• Covers risk assessment and the use of omics and computational technologies in mechanistic and predictive toxicology
• Offers clinical interventions and managed care strategies for acute poisoning

Product Details:

• Publisher: Elsevier Science
• Publication Date: March 23, 2023
• Language: English
• ISBN: 9780443158407 (hardcover) | 9780443158414 (e-book)