Tissue Barriers in Disease, Injury and Regeneration: A Comprehensive Guide

Authored by Nikolai V. Gorbunov, this groundbreaking book delves into the molecular and cellular fundamentals of homeostatic and defense responses of tissue barriers. Specifically, it explores the damaging impacts of pathogens and engineered nanomaterials on these crucial biological barriers.

The Role of Key Cell Types in Tissue Barrier Response

The book places special emphasis on the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid, and reticuloendothelial cells in bridging the effects of ambient factors, medical treatments, and drug delivery systems on barrier integrity, tissue/organ functions, and metabolic status.

These cells play a crucial role in the development of reactions that maintain the delicate balance between tissue homeostasis and defense responses. By understanding their functions, researchers and clinicians can gain valuable insights into the mechanisms underlying various diseases and injuries.

Tissue Remodeling and Regeneration: The Role of Progenitor Cells

The book also examines the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, vasculature of blood-tissue barriers, and mucosa and external epithelium. This knowledge is essential for the development of novel therapeutic strategies targeting tissue regeneration and repair.

By exploring the complex interplay between tissue barriers, ambient factors, and medical interventions, this book provides a comprehensive understanding of the molecular and cellular mechanisms underlying various diseases and injuries. It serves as an invaluable resource for researchers, clinicians, and students seeking to advance their knowledge in this critical field.

Book Details:

• Publisher: Elsevier

• 1st edition: July 7, 2021

• Language: English

• Paperback: 206 pages

• ISBN-10: 0128185619

• ISBN-13: 978-0128185612