Revolutionize Drug Delivery with Physiologically-Based Models

Edited by leading experts in the field, Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics provides a comprehensive discussion on the application of physiologically- and physicochemical-based models to guide drug delivery. This book offers a thorough exploration of drug delivery options to achieve target profiles and approaches as defined by physical and pharmacokinetic models.

Comprehensive Coverage of Drug Delivery Options

The book provides an in-depth overview of drug absorption and physiological models, including chapters on oral delivery routes with a focus on both Physiologically-Based Pharmacokinetic (PBPK) and multiple dosage form options. Additionally, it explains the pharmacokinetics of the formulation of drugs delivered by systemic transdermal routes.

Pulmonary and Mucosal Delivery of Drugs

The book also delves into the biological and delivery approaches to pulmonary and mucosal delivery of drugs, making it a valuable resource for researchers and industrial scientists. Emergency care settings are also described, with explorations of the relationship between parenteral infusion profiles and PK/PD.

The Future of Drug Delivery

The editors provide insights into the future of drug delivery, including discussions on virtual experiments to elucidate mechanisms and approaches to drug delivery and personalized medicine. This comprehensive guide will benefit researchers, industrial scientists, graduate students, and postdoctoral students in the area of pharmaceutical science and engineering.

Key Takeaways

• A thorough introduction to the utility of mathematical models in drug development and delivery
• An exploration of the techniques and applications of physiologically based models to drug delivery
• Discussions of oral delivery and pharmacokinetic models and oral site-directed delivery
• A review of integrated transdermal delivery and pharmacokinetics in development
• An examination of virtual experiment methods for integrating pharmacokinetic, pharmacodynamic, and drug delivery mechanisms
• Alternative endpoints to pharmacokinetics for topical delivery

Get ahead in the field of pharmaceutical science and engineering with Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics. This comprehensive guide is a must-have for formulators, pharmacokineticists, and clinical pharmacologists.