Understanding the Lungs: The Crucial Interface Between Body and Environment

The lungs are the vital organs responsible for gas exchange between the body and the external environment. However, dysfunction of upper airway epithelium and smooth muscle cells can lead to the pathogenesis of various respiratory diseases, including asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other conditions. This can result in airway inflammation and narrowing, significantly impacting overall health.

The Importance of Lung Cells in Health and Disease

Injury to alveolar epithelium and endothelium causes an influx of neutrophils and protein-rich fluid from circulation, resulting in edema and disruption of gas exchange. Moreover, immune cells, such as alveolar macrophages and lymphocytes, play critical roles in maintaining lung function. A comprehensive understanding of the role of lung cells in physiological and pathological conditions is crucial for the development of novel therapeutics.

The Impact of Nutrition and Pollution on Lung Health

A healthy diet and a clean environment are essential for maintaining optimal lung function. Nutrition plays a vital role in supporting lung health, while air pollution has a detrimental effect on lung function. Exposure to pollutants can exacerbate respiratory diseases, highlighting the need for awareness and action to mitigate the effects of pollution on lung health.

This book, authored by Yutong Zhao, brings together contributions from leading researchers to provide a comprehensive understanding of the lungs as an interface between the body and the environment. By highlighting the underlying mechanisms of lung diseases and the importance of nutrition and environment, this book contributes significantly to the development of novel therapeutics for respiratory diseases.

Key Features:

• Explores the crucial role of the lungs as an interface between the body and the environment.
• Describes the underlying mechanisms of lung diseases, including asthma, COPD, and cystic fibrosis.
• Emphasizes the importance of nutrition in maintaining lung health and the adverse effects of pollution.
• Includes contributions from leading researchers in the field of respiratory medicine.

Publisher: CRC Press
Publication Date: February 20, 2024
Language: English
ISBN: 9781032409023, 9781003833161