Genetics and Neurobiology of Down Syndrome: A Comprehensive Review

Written by esteemed author Bani Bandana Ganguly, this book provides an in-depth exploration of the genetic etiology and mechanisms of trisomy 21, offering a thorough understanding of Down Syndrome.

History, Clinical Features, and Health Consequences

The book delves into the history of Down Syndrome, its clinical features, and the various health consequences associated with it. This includes a detailed examination of the physical features, cognitive symptoms, and neurologic symptoms that individuals with Down Syndrome may exhibit.

Genetic Counseling and Prenatal Screening: Weighing the Pros and Cons

Ganguly also discusses the importance of genetic counseling, highlighting the pros and cons of prenatal screening and testing. The book explores the associated ethical issues, providing readers with a comprehensive understanding of the complex decisions involved.

Societal and Demographic Aspects: Understanding the Bigger Picture

The author sheds light on the societal and demographic aspects of Down Syndrome, examining the impact of the condition on individuals, families, and communities. This unique perspective provides readers with a deeper understanding of the syndrome’s far-reaching consequences.

The Link Between Down Syndrome and Alzheimer’s: Uncovering the Connection

One of the book’s most fascinating aspects is its exploration of the link between Down Syndrome and susceptibility to Alzheimer’s disease, as well as early brain aging. Ganguly’s research provides valuable insights into this complex relationship, shedding light on potential therapeutic developments.

Future Directions: Unraveling the Mysteries of Trisomy 21

In conclusion, the book looks to the future, discussing potential therapeutic developments and the direction of ongoing research. With its comprehensive coverage of the genetic etiology and mechanisms of trisomy 21, this book is an indispensable resource for researchers, medical professionals, and families affected by Down Syndrome.

Book Details:
Publisher: Elsevier Science
Publication Date: August 21, 2022
Language: English
ISBN: 9780323904568, 9780323904575