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By Ronald Kaminsky, a renowned expert in the field, Human and Animal Filariases delves into the complexities of filarial parasites, shedding light on the severe diseases they cause in humans and animals. Filariae, a family of parasitic worms, are responsible for lymphatic filariasis (elephantiasis), onchocerciasis (river blindness), and dirofilariasis (heartworm disease) among others.
The World Health Organization has classified filariases as neglected tropical diseases, emphasizing the need for effective control measures. The burden of these diseases is substantial, with blindness and disfiguration affecting millions of individuals and placing a significant strain on healthcare systems in tropical regions.
This comprehensive book takes a multifaceted approach to understanding and addressing filarial infections. It begins by examining the current state of diagnosis and chemotherapy, highlighting the increasing resistance to available antifilarial drugs.
The book then delves into strategies for the discovery of novel drugs, including assay development, target validation, and required drug product profiles. Furthermore, it explores alternative and supplementary approaches to combat filarial parasites, such as vector control and vaccination.
Human and Animal Filariases is an indispensable reference for parasitologists, veterinarians, and professionals in the pharmaceutical industry and public health agencies. It provides practical insights and expert knowledge from leading academic institutions and industry experts.
With its integrated approach, this book offers a unique perspective on the diagnosis, treatment, and control of filarial infections, making it an essential resource for anyone working to eradicate these debilitating diseases.
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