Fragile X and Related Autism Spectrum Disorders: A Comprehensive Review

Fragile X and Related Autism Spectrum Disorders, Volume 172 in the International Review on Neurobiology series, is a groundbreaking publication that delves into the latest advances in the field. This volume presents a collection of insightful chapters that explore various aspects of Fragile X Syndrome and its connection to Autism Spectrum Disorder.

The Dopamine Hypothesis of Autism Spectrum Disorder: A Comprehensive Analysis of the Evidence

This chapter provides an in-depth analysis of the dopamine hypothesis, shedding light on the potential role of dopamine in the pathogenesis of Autism Spectrum Disorder. It offers a comprehensive review of the existing evidence, highlighting the complexities and controversies surrounding this hypothesis.

A Review of the Use of Psychotropic Medication to Address Challenging Behavior in Neurodevelopmental Disorders

This review chapter examines the use of psychotropic medications in managing challenging behaviors associated with neurodevelopmental disorders, including Fragile X Syndrome and Autism Spectrum Disorder. It discusses the efficacy, safety, and ethical considerations of these treatments, providing valuable insights for healthcare professionals and researchers alike.

Lipid Metabolism Alterations in Fragile X Syndrome and Other Neurodevelopmental Disorders

This chapter explores the alterations in lipid metabolism observed in Fragile X Syndrome and other neurodevelopmental disorders. It delves into the potential mechanisms underlying these changes and discusses their implications for our understanding of the pathogenesis of these conditions.

Genesis, Modelling, and Methodological Remedies to Autism Heterogeneity

This chapter addresses the issue of heterogeneity in Autism Spectrum Disorder, discussing the genetic and environmental factors that contribute to its complex phenotype. It also presents various modelling approaches and methodological strategies aimed at better understanding and addressing this heterogeneity.

Toward an Understanding of the Role of the Exposome on Fragile X Phenotypes

This chapter focuses on the exposome, or the totality of environmental exposures an individual experiences throughout their lifetime. It explores the potential impact of the exposome on the development and expression of Fragile X Syndrome, highlighting the need for further research in this area.

Glial-Mediated Dysregulation of Neurodevelopment in Fragile X Syndrome

This chapter examines the role of glial cells in the neurodevelopmental abnormalities observed in Fragile X Syndrome. It discusses the potential mechanisms by which glial cells contribute to the pathogenesis of this condition, providing new insights into the complex interplay between glial and neuronal cells in neurodevelopment.