Fragile X and Related Autism Spectrum Disorders: A Comprehensive Review

Fragile X and Related Autism Spectrum Disorders, Volume 172 in the International Review on Neurobiology series, is a comprehensive compilation of the latest advances in the field. This new volume presents a range of insightful chapters that delve into various aspects of Fragile X Syndrome and its connection to Autism Spectrum Disorder.

The Dopamine Hypothesis of Autism Spectrum Disorder: A Comprehensive Analysis of the Evidence

This chapter provides an in-depth analysis of the dopamine hypothesis in relation to Autism Spectrum Disorder. It explores the role of dopamine in the development and progression of the disorder, shedding light on potential therapeutic interventions.

A Review of the Use of Psychotropic Medication to Address Challenging Behavior in Neurodevelopmental Disorders

This review examines the use of psychotropic medications in managing challenging behaviors associated with neurodevelopmental disorders. It discusses the efficacy, safety, and potential side effects of these medications, providing valuable insights for healthcare professionals and researchers alike.

Lipid Metabolism Alterations in Fragile X Syndrome and Other Neurodevelopmental Disorders

This chapter focuses on the alterations in lipid metabolism observed in Fragile X Syndrome and other neurodevelopmental disorders. It highlights the potential implications of these alterations on the development and progression of these disorders, as well as possible therapeutic strategies.

Genesis, Modelling, and Methodological Remedies to Autism Heterogeneity

This chapter addresses the issue of heterogeneity in Autism Spectrum Disorder, exploring the genetic and environmental factors that contribute to this variability. It also discusses various modelling approaches and methodological remedies aimed at better understanding and addressing this heterogeneity.

Toward an Understanding of the Role of the Exposome on Fragile X Phenotypes

This chapter delves into the role of the exposome in shaping Fragile X phenotypes. It examines the impact of environmental factors on the expression of the Fragile X gene and the development of related disorders, providing insights into potential preventive and therapeutic measures.

Glial-Mediated Dysregulation of Neurodevelopment in Fragile X Syndrome

This chapter explores the role of glial cells in the dysregulation of neurodevelopment observed in Fragile X Syndrome. It discusses the potential mechanisms by which glial cells contribute to the development and progression of the disorder, highlighting potential therapeutic targets.