Neuropsychiatric Disorders and Epigenetics: A Comprehensive Guide

Neuropsychiatric Disorders and Epigenetics, Second Edition, is a groundbreaking reference that delves into the intricate relationship between epigenetics and common neuropsychiatric disorders. This comprehensive volume, authored by Jacob Peedicayil, brings together leading experts in their respective fields to provide an in-depth exploration of the epigenetic aspects of various neuropsychiatric disorders.

Understanding Epigenetics in Neuropsychiatric Disorders

Epigenetics, the study of heritable changes in gene function that occur without a change in the underlying DNA sequence, plays a pivotal role in the development and progression of neuropsychiatric disorders. The volume covers a wide range of disorders, including addiction, anxiety, and autism spectrum disorders, shedding light on the epigenetic mechanisms involved and potential therapeutic interventions.

Epigenetic Mechanisms and Their Impact

The book delves into the full range of epigenetic mechanisms, including DNA modification, histone post-translational modification, chromatin organization, and non-coding RNA. These mechanisms are crucial for understanding how environmental stimuli can influence epigenetic states, leading to the development of neuropsychiatric disorders.

Therapeutic Interventions and Future Directions

A significant focus of the book is on potential epigenetic interventions, highlighting the importance of environmental stimuli in shaping epigenetic states relevant to disease. The volume also explores recent research advances enabled by genomic technologies, as well as promising directions for ongoing investigation in the field of neuropsychiatric disorders and epigenetics.

New Edition Highlights

The second edition of Neuropsychiatric Disorders and Epigenetics has been fully updated to reflect the latest research findings and therapeutic approaches. New chapters have been added, covering topics such as epigenetics and anxiety disorders, epigenetics and neuroimaging in neuropsychiatric disorders, genome-wide approaches to epigenetic research, and the epigenetics of spinal muscular atrophy.

Key Features

This comprehensive reference includes:

• Extensive use of diagrams, illustrations, tables, and graphical abstracts to reinforce understanding
• Chapter contributions from leading global experts in the field
• A detailed analysis of the effects of environmental stimuli on epigenetic states correlating with neuropsychiatric disease induction
• A review of the epigenetic basis for common neuropsychiatric disorders, guiding translational therapies for clinicians and mechanistic studies for scientists

Neuropsychiatric Disorders and Epigenetics, Second Edition, is an indispensable resource for researchers, clinicians, and students seeking to understand the complex interplay between epigenetics and neuropsychiatric disorders. By shedding light on the epigenetic mechanisms underlying these disorders, this volume empowers new research, clinical translation, and pharmacological advances, highlighting promising directions for ongoing investigation in the field.