Updated Insights into Neoplastic Hematology: A Comprehensive Guide

By Wojciech Gorczyca, the fourth edition of this seminal work presents an updated and expanded text, reflecting the latest advances in neoplastic hematology. The rapidly expanding application of next-generation sequencing has significantly enhanced the field, allowing for more reliable diagnoses and the identification of early changes such as monoclonal B-cell lymphocytosis or clonal hematopoiesis of indeterminate potential (CHIP). Moreover, these advances have led to the discovery of mutations or phenotypic changes in tumors that can be targeted by mutation-specific or antigen-specific drugs.

This edition incorporates the updated WHO classification of hematopoietic tumors and new immunophenotypic and molecular markers, providing a thorough pathologic overview of hematologic neoplasms while focusing on flow cytometric features. Special emphasis has been placed on hematological neoplasms with crucial clinical significance, such as acute promyelocytic leukemia, other acute leukemias, and difficult areas in flow cytometry. The flow cytometric features in AML, MDS, CMML, CLL, and measurable residual disease have been significantly expanded, with many new comparative tables, illustrations, and diagrams of algorithmic approaches.

Published by CRC Press on December 12, 2022, this book is available in English and offers a comprehensive guide for researchers, clinicians, and students in the field of neoplastic hematology. With its updated information and expanded content, this book is an essential resource for those seeking to understand the latest developments in the diagnosis and treatment of hematological neoplasms.

ISBN: 9781032055251, 9781000644807