Unveiling the Enigma of Peroxiporins: A Key to Efficient Redox Signaling

By Iria Medrao-Fernandez

Redox signaling, a process that has evolved over time, is a crucial mechanism in aerobic organisms. It involves the transformation of oxygen molecules into water, which yields toxic radical intermediates known as reactive oxygen species (ROS). This paradoxical process has been harnessed by evolution to transmit information efficiently within the cell. The regulation of this process is meticulously organized, with a key element being the physical separation of sources and targets into different cell compartments.

A pivotal player in this intricate dance of redox signaling is the peroxiporin, a protein that transports hydrogen peroxide across biological membranes. These channels are strategically positioned, ensuring that the signal is transmitted safely and efficiently from emitters to receptors. Peroxiporins are the unsung heroes of cellular communication, operating in the delicate balance between life and death.

This book provides a comprehensive overview of the discovery and characterization of peroxiporins, shedding light on the history of their identification and the key findings related to hydrogen peroxide transport across biological membranes. It delves into the complex cartography of redox signaling in crowded cells, offering insights into the spatial organization and regulation of this process.

With lavish illustrations and comprehensive images, this book is an essential resource for researchers, students, and educators seeking to understand the intricacies of cellular communication. It highlights recent findings, outstanding controversies, and open questions in the field, providing a roadmap for future research and exploration.

Published by CRC Press, this book is a testament to the relentless pursuit of knowledge and understanding in the field of cellular biology. It serves as a beacon for those seeking to unravel the mysteries of life at the molecular level, offering a glimpse into the fascinating world of peroxiporins and their role in redox signaling.