Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy: A Comprehensive Guide

Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy is a groundbreaking imaging modality that allows for real-time metabolic imaging in cells, animals, and humans. It uses non-toxic, endogenous contrast agents that are hyperpolarized, resulting in a significant increase in sensitivity, up to 100,000-fold. This technique does not require ionizing radiation and is currently being applied in various human trials. Its primary application is metabolic imaging, but it can also measure perfusion, pH, and necrosis.

Understanding the Principles of Hyperpolarized 13C MRI

This book provides a comprehensive overview of the principles of hyperpolarized 13C MRI, the necessary equipment for conducting studies, how to interpret the results, and an overview of current biomedical applications. It is an essential resource for engineers, scientists, and clinicians in radiology and biomedical imaging who wish to understand this technology.

The Physics and Hardware of Dissolution Dynamic Nuclear Polarization

The book delves into the physics and hardware of dissolution dynamic nuclear polarization, explaining how hyperpolarized carbon-13 agents behave and how to image them. It offers detailed guidance on experimental design and data interpretation, helping readers to fully understand the potential of this imaging modality.

Applications of Hyperpolarized Carbon-13 MR

Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy identifies promising and potential applications of hyperpolarized carbon-13 MR, including its use in cancer research, cardiovascular disease, and neurological disorders. By providing insights into the current state and future directions of this technology, the book is an invaluable resource for those working in the field of biomedical imaging.