Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition

Authored by Martin Wehling, the third edition of “Principles of Translational Science in Medicine: From Bench to Bedside” offers a comprehensive update on the significant advancements in the translation of research into medically relevant results and therapeutics. This book provides an in-depth discussion on biomarkers, early human trials, and networking models, as well as institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics.

New Chapters and Key Topics

This edition includes new chapters on:

• Translation in Oncology
• Biologicals
• Orphan Drugs

These chapters provide a systematic approach to translational medicine, making the book an ideal guide for biomedical scientists. The content is written by worldwide experts in their respective fields.

Key Features

This book includes:

• State-of-the-art principles, tools such as biomarkers and early clinical trials, algorithms of translational science in medicine
• In-depth description of special translational aspects in the currently most successful areas of clinical translation, namely oncology and immunology
• Covers status of institutionalization of translational medicine, networking structures and outcomes at the level of marketing authorization

By providing a comprehensive overview of translational science in medicine, this book serves as a valuable resource for researchers, scientists, and healthcare professionals seeking to advance their knowledge and understanding of this rapidly evolving field.