Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease: A Comprehensive Review

By Grazyna Soderbom, a renowned author in the field of neurodegenerative diseases, this book provides an in-depth analysis of recent developments in intervention trials for Alzheimer’s and Parkinson’s diseases. It also delves into the overlap between metabolic and neurodegenerative diseases, focusing on how they impact mitochondrial function and bioenergetics.

Key Topics Covered

• Brain Glucose and Ketone Utilization in Brain Ageing and Neurodegenerative Diseases: This section explores the role of glucose and ketones in brain function and how their utilization changes with age and in the presence of neurodegenerative diseases.
• The Mitochondrial Hypothesis: Dysfunction, Bioenergetic Defects, and the Metabolic Link to Alzheimer’s Disease: This topic discusses the mitochondrial hypothesis, which suggests that mitochondrial dysfunction is a primary cause of Alzheimer’s disease. It delves into the bioenergetic defects that contribute to this hypothesis and the metabolic link between Alzheimer’s and mitochondrial function.
• The Metabolic Impact on Neuroinflammation and Microglial Modulation in Neurodegenerative Diseases: This section examines the impact of metabolic changes on neuroinflammation and how these changes modulate microglial function in neurodegenerative diseases.
• The Impact of Circadian and Diurnal Rhythms on Cellular Metabolic Function and Neurodegenerative Diseases: This topic covers the effects of circadian and diurnal rhythms on cellular metabolic function and how these rhythms influence neurodegenerative diseases.

Why This Book Matters

Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease is a crucial resource for researchers, scientists, and healthcare professionals working in the field of neurodegenerative diseases. It provides a comprehensive overview of the current status of Alzheimer’s and Parkinson’s diseases, as well as future research directions. The book’s focus on the metabolic hypothesis and its implications for understanding and treating these diseases makes it a valuable addition to any medical or scientific library.

Author Bio

Grazyna Soderbom is a leading expert in the field of neurodegenerative diseases, with a particular focus on the metabolic and bioenergetic aspects of these conditions. Her work has contributed significantly to our understanding of the underlying mechanisms of Alzheimer’s and Parkinson’s diseases, and she continues to be at the forefront of research in this area.