Oral Delivery of Therapeutic Peptides and Proteins: A Comprehensive Overview

Oral Delivery of Therapeutic Peptides and Proteins provides a detailed insight into the journey scientists undertake to achieve protein and peptide oral delivery. The book highlights the physiological challenges that must be considered, in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research.

Formulation Technologies for Protein and Peptide Delivery

Primary topics include the formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their limitations in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport.

Target Audience

Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a valuable resource.

Key Features

Demonstrates how proteins and peptides transport throughout the gastrointestinal tract and how to evaluate their biological fate when encapsulated into certain delivery systems. Examines developing technologies to improve future oral bioavailability. Includes the in vitro and preclinical techniques needed for development.

Publication Details

Published by Elsevier Science on August 18, 2022. Language: English. ISBN: 9780128210611, 9780128210604.