The Neurobiology of Aging and Alzheimer Disease in Down Syndrome

Author: Elizabeth Head

Publication Date: August 31, 2021

Language: English

ISBN: 9780128188453, 9780128188460

Publisher: Elsevier Science

Summary: This book provides a multidisciplinary approach to understanding aging and Alzheimer disease in Down syndrome, focusing on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. It offers detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts.

Target Audience: Researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and new investigators to the aging and Alzheimer/Down syndrome arena.

Key Features: Discusses the complexities involved with aging and Alzheimer’s disease in Down syndrome, summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age, serves as a learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research.

Why This Book Matters: This book is a must-have resource for those working in the field of aging and Alzheimer’s disease, providing comprehensive insights into the complexities of Down syndrome and its relationship with aging and neurodegeneration. It offers a unique perspective on the management and prevention of Alzheimer’s disease in individuals with Down syndrome, promoting healthier aging and better quality of life.