Epigenetics in Human Disease: A Comprehensive Guide to Understanding and Application

Epigenetics in Human Disease, Third Edition, is a comprehensive resource that delves into the complexities of epigenetic mechanisms and their role in various diseases and conditions. Authored by renowned expert Trygve O. Tollefsbol, this book provides an in-depth exploration of epigenetics in human disease, covering topics ranging from molecular mechanisms and epigenetic technology to clinical translation and therapeutic interventions.

Understanding Epigenetic Mechanisms in Disease

This book examines the latest research in epigenetic disease mechanisms, including cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders, and cardiovascular disease. The author presents a clear understanding of the fundamental basis of epigenetics and its applications in therapeutic interventions for epigenetic-based disorders.

Current Research and Clinical Breakthroughs

The Third Edition of Epigenetics in Human Disease features fully revised and up-to-date content, covering topics of current interest in epigenetic disease research. These include:

• Stem cell epigenetic therapy
• Bioinformatic analysis of NGS data
• Epigenetic mechanisms of imprinting disorders
• MicroRNA in cancer
• Epigenetic approaches to control obesity
• Epigenetics and airway disease
• Epigenetics in cardiovascular disease

Online Epigenetic Tools and Datasets

The book also explores online epigenetic tools and datasets, providing researchers and clinicians with valuable resources for advancing their research and practice.

Early-Life Programming and Epigenetic Disease

Furthermore, the book examines the early-life programming of epigenetics in age-related diseases, including the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer’s disease, and respiratory diseases.

Features and Benefits

Each chapter in Epigenetics in Human Disease includes:

• Chapter summaries for easy reference
• Definitions to clarify key concepts
• Vibrant imagery and figures to reinforce understanding
• Step-by-step methods and disease research case studies to put book concepts into practice

With contributions from leading international investigators involved in translational epigenetic research and therapeutic applications, this book integrates methods and applications with fundamental chapters on epigenetics in human disease, along with an evaluation of recent clinical breakthroughs.

Presented in a clear and concise manner, Epigenetics in Human Disease is an essential resource for researchers, clinicians, and students seeking to understand the complexities of epigenetics and its role in human disease.

Product Details:

Publisher: Elsevier Science

Language: English

ISBN: 9780443218118, 9780443218125

Publication Date: October 9, 2023