Unlock the Power of Open Access Databases and Datasets for Drug Discovery

Stay ahead in the rapidly evolving field of data-driven drug discovery with Open Access Databases and Datasets for Drug Discovery, a comprehensive guide to the vast array of freely accessible databases and datasets available to pharmaceutical researchers today.

This timely resource provides an in-depth overview of 90 open-source databases and datasets, covering all aspects of drug design, development, and discovery. The book expertly analyzes the applicability of open-source data for drug discovery and development, comparing their usefulness with commercially available tools.

Comprehensive Coverage of Open Access Databases

The book delves into the most relevant databases for:

• Small molecules, drugs, and drug-like substances
• Ligand design and protein 3D structures (both experimental and calculated)
• Human drug targets and diseases

Each database is described in detail, including practical examples of how to access and work with the data. The book is divided into three parts, focusing on databases for small molecules, macromolecular targets and diseases, and integrating open-source tools into the academic and industrial drug discovery and development process.

Expert Insights and Practical Applications

Edited by experts with extensive experience in the field, Open Access Databases and Datasets for Drug Discovery provides valuable insights into:

• An extensive listing of open access databases and datasets for computer-aided drug design
• PubChem as a chemical database for drug discovery
• DrugBank Online and bioisosteric replacement for drug discovery supported by the SwissBioisostere database
• The Protein Data Bank (PDB) and macromolecular structure data supporting computer-aided drug design
• The SWISS-MODEL repository of 3D protein structures and models
• PDB-REDO in computational aided drug design (CADD) and using Pharos/TCRD for discovering druggable targets

This essential reference is unmatched in scope, providing a thorough review of small and large open data sources relevant for rational drug design. Open Access Databases and Datasets for Drug Discovery is a must-have for medicinal and pharmaceutical chemists, as well as scientists involved in drug discovery and development.

Published by Wiley, this book is available in English and can be identified by the following ISBN numbers: 9783527348398 and 9783527830473.