Natural Products and Their Bioactives in Antidiabetic Drug Discovery

By Kanti Bhooshan Pandey, Maitree Suttajit, and Pinar Atukeren

This comprehensive resource enables researchers to effectively understand and utilize bioactive compounds to target, prevent, and manage diabetes. Natural Products and Their Bioactives in Antidiabetic Drug Discovery bridges the gap between public research institutes and private companies working to find drugs to treat diabetes.

Overview of Recent Research in Antidiabetic Drug Discovery

The book provides an overview of recent research in new drug discovery against diabetic complications based on bioactives from natural products (NPs). It includes case studies and illustrated examples in relevant chapters to aid in reader comprehension.

Structure and Content

The text is divided into four parts:

• Part one presents fundamental concepts of diabetes mellitus (DM) and recent drug discovery progress, along with the various druggable targets and challenges.
• Part two covers bioactive compounds targeting Type-1 Diabetes.
• Part three focuses on Type-2 Diabetes.
• Part four addresses gestational DM prevention and management with natural compounds.

Expert Insights and Topics Covered

Written by a global team of experts in the field, this book covers a range of topics, including:

• Obesity as a risk factor in patients with T1DM and the possible role of nutritional therapy in its management.
• The use of natural non-insulin drugs as a novel approach to enhance therapeutic outcomes against T1DM.
• The effectiveness of functional foods in intervening diabetic complications and realistic results in clinical trials.
• The implementation of nanotechnology in improving the bioavailability and reducing the threshold dose of bioactive compounds.
• Various antidiabetic mechanisms of action of different polyphenols and the immunomodulatory role of NPs bioactives in T1DM therapy.
• The effects of natural products on the genetics of gestational diabetes.

Essential Resource for Researchers and Professionals

Natural Products and Their Bioactives in Antidiabetic Drug Discovery is an essential resource for researchers and professionals involved in drug discovery and development, healthcare, medicinal chemistry, phytochemistry, plant science, and toxicology.

Product Details:

• Publisher: Wiley
• Edition: 1st edition (August 1, 2023)
• Language: English
• Hardcover: 352 pages
• ISBN-10: 1119983312
• ISBN-13: 978-1119983316