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Edited by Nima Rezaei and Niloufar Yazdanpanah, this book provides a cutting-edge overview of the latest advances in translational neuroimmunology, focusing on the bench-to-bedside studies of neurological disorders with immunological etiologies.
The book covers the fundamental principles of neuroimmunology, autoimmune, and autoinflammatory neurological disorders, with a special emphasis on multiple sclerosis. It delves into the immunopathology, genetics, epigenetics, microbiome, diagnosis, and treatment of multiple sclerosis, exploring the intricate relationships between the immune system and the central nervous system.
The book is divided into ten comprehensive chapters, each tackling a distinct aspect of neuroimmunology. One chapter is dedicated to the role of pericytes in neuroinflammation, while the final chapters discuss the neurologic manifestations, diagnostic approaches, and treatments of various neuroimmune disorders, as well as the valuable insights gained from translational research on non-human primates and zebrafish.
This volume is designed to be an accessible and practical resource for immunologists, neurologists, and researchers in translational biomedical research. It encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease, with a focus on understanding and therapeutically manipulating immunological responses to injury, degeneration, and autoimmunity in the central nervous system.
By exploring the changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases, this book provides a deeper understanding of the complex interplay between the immune system and the nervous system, ultimately aiding in the development of novel therapeutic strategies for neuroimmunological disorders.
Book Details: Publisher: Academic Press; 1st edition (July 14, 2023) | Language: English | Paperback: 540 pages | ISBN-10: 0323858414 | ISBN-13: 978-0323858410
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