Understanding Melanoma: A Comprehensive Guide

Edited by esteemed professionals Drs. Brian R. Gastman and Michael W. Neumeister, this issue of Clinics in Plastic Surgery delves into the intricacies of melanoma, providing a comprehensive overview of risk factors, prevention, biology, and treatment options.

Melanoma Risk Factors and Prevention

Learn about the factors that increase your risk of developing melanoma and how to prevent this potentially life-threatening condition.

Biology and Signaling Pathways of Melanoma

Dive into the complex biology and signaling pathways of melanoma, understanding how this cancer develops and progresses.

Immunobiology of Melanoma

Explore the role of the immune system in melanoma, including how it can be harnessed for treatment.

Clinical Diagnosis and Classification

Discover the methods used to diagnose and classify melanoma, including clinical and histopathological approaches.

AJCC Staging and Other Platforms to Assess Prognosis and Risk

Understand how the American Joint Committee on Cancer (AJCC) staging system and other platforms are used to assess the prognosis and risk of melanoma.

Current Treatment Guidelines of Primary Melanoma

Get up-to-date information on the current treatment guidelines for primary melanoma, including wide excision and sentinel node biopsy.

Dermatologic Follow-up and Assessment of Suspicious Lesions

Learn about the importance of regular dermatologic follow-ups and how to assess suspicious skin lesions for potential melanoma.

Immunotherapy of Melanoma

Explore the various immunotherapies available for treating melanoma, including checkpoint inhibitors and cancer vaccines.

Targeted Therapies for Melanoma

Discover the targeted therapies that have been developed to treat specific genetic mutations associated with melanoma.

Non-Operative Intra-Tumoral Therapies

Understand the non-operative intra-tumoral therapies available for treating melanoma, including talimogene laherparepvec (Imlygic).

Role of Radiation for Locoregional and Distant Metastatic Melanoma

Learn about the role of radiation therapy in treating both locoregional and distant metastatic melanoma.

Adjuvant and Neoadjuvant Therapy for Melanoma

Explore the adjuvant and neoadjuvant therapies used to treat melanoma, including chemotherapy, immunotherapy, and targeted therapy.

Surgery of the Nodal Basins for Trunk and Extremity Melanoma

Understand the surgical approaches used to treat nodal basins for trunk and extremity melanoma.

Extirpative Considerations of Melanoma of the Head and Neck

Learn about the extirpative considerations for treating melanoma of the head and neck, including surgical techniques and reconstruction options.

Treatment of Lentigo Maligna of the Head and Neck

Discover the treatment options available for lentigo maligna, a subtype of melanoma that occurs on the head and neck.

Reconstructive Considerations of Melanoma of the Head and Neck

Explore the reconstructive considerations following the removal of melanoma from the head and neck, including various surgical techniques.

Melanoma of the Hands and Feet

Understand the unique challenges and treatment approaches for melanoma that occurs on the hands and feet.

Rare Variants of Melanoma

Learn about the rare variants of melanoma, including desmoplastic melanoma, acral lentiginous melanoma, and others.

Emerging Therapies for Melanoma

Stay updated on the latest emerging therapies for melanoma, including new immunotherapies, targeted therapies, and combination treatments.