Optimizing Drug Selectivity in Medicinal Chemistry: A Comprehensive Guide

Edited by Norbert Handler, Helmut Buschmann, Raimund Mannhold, and Jrg Holenz, this book provides a comprehensive overview of the impact of targeting multiple targets on the drug development process. It serves as a broad survey of current and future strategies for drug selectivity in medicinal chemistry, encompassing both theoretical and practical aspects.

Different strategies are presented and evaluated, including various design approaches, merged multiple ligands, discovery technologies, and a range of successful examples of unselective drugs from major disease areas. This handbook is essential for every medicinal and pharmaceutical chemist, offering a wide-ranging view of an emerging new paradigm in drug development.

Series: Methods and Principles in Medicinal Chemistry

Format: Hardcover

Pages: 536

Publisher: Wiley-VCH; 1 edition (February 27, 2018)

Language: English

ISBN-10: 3527335382

ISBN-13: 978-3527335381

Dimensions: 6.7 x 6.7 x 9.4 inches