Optimizing Drug Selectivity in Medicinal Chemistry: A Comprehensive Guide

By Norbert Handler, Helmut Buschmann, Raimund Mannhold, Jrg Holenz, and more

Publication Date: February 27, 2018

Pages: 536

ISBN: 978-3527335381

Dimensions: 6.7 x 6.7 x 9.4 inches

Series: Methods and Principles in Medicinal Chemistry

Format: Hardcover

Language: English

Publisher: Wiley-VCH

Edition: 1

Product Description:

This book provides a comprehensive overview and compilation for medicinal chemists, discussing the effects of aiming for multiple targets on the entire drug development process. It offers a broad survey of current and future strategies for drug selectivity in medicinal chemistry, covering both theoretical and practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies, and a broad range of successful examples of unselective drugs taken from all major disease areas.

With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist. It serves as a valuable resource for those working in the field of drug development, providing insights into the latest trends and techniques in optimizing drug selectivity.

Key Features:

• Comprehensive overview of current and future strategies for drug selectivity in medicinal chemistry
• Covers both theoretical and practical aspects of drug development
• Includes successful examples of unselective drugs from all major disease areas
• Essential reading for medicinal and pharmaceutical chemists
• Provides insights into the latest trends and techniques in optimizing drug selectivity

Target Audience:

This book is primarily intended for medicinal and pharmaceutical chemists working in the field of drug development. It is also suitable for researchers, scientists, and students interested in the latest trends and techniques in optimizing drug selectivity.

Content:

The book is divided into several chapters, each focusing on a different aspect of drug selectivity. It begins with an introduction to the importance of drug selectivity in medicinal chemistry, followed by chapters on various design approaches, merged multiple ligands, and discovery technologies. The book also includes a section on successful examples of unselective drugs from various disease areas, providing valuable insights into the practical applications of the strategies discussed.

Conclusion:

Optimizing drug selectivity is a crucial aspect of drug development, and this book provides a comprehensive guide for medicinal chemists working in this field. With its broad survey of current and future strategies, it serves as a valuable resource for those looking to improve their understanding of the latest trends and techniques in optimizing drug selectivity.