Non-coding RNA Transcripts in Cancer Therapy: A Comprehensive Guide

By Gautam Sethi, “Non-coding RNA Transcripts in Cancer Therapy: Pre-clinical and Clinical Implications” offers a fresh perspective on the role of non-coding RNAs, including microRNAs, long non-coding RNAs, and circular RNAs in cancer. This book focuses on cancer, a leading cause of death worldwide, after cardiovascular diseases. It provides in-depth information on the biogenesis and biological functions of non-coding RNAs, their regulation of gene expression at transcriptional and post-transcriptional levels, and their impact on key molecular mechanisms such as proliferation, metastasis, epithelial-to-mesenchymal transition, apoptosis, and autophagy.

The book delves into the biogenesis and biological functions of microRNAs, long non-coding RNAs, and circular RNAs in physiological conditions. It also explores their roles in regulating proliferation, metastasis, and therapy response, including drug resistance and radio-resistance. Furthermore, the function of exosomal non-coding RNAs in the diagnosis and prognosis of cancer patients is discussed, making the book a comprehensive resource for researchers and clinicians alike.

Published by World Scientific Pub Co Inc on April 25, 2023, this hardcover book contains 376 pages and is available in English. The ISBN-10 is 9811267383, and the ISBN-13 is 978-9811267383. This book is an essential read for anyone interested in the latest developments in cancer research and therapy.