Perinatal Pharmacology: A Comprehensive Review of Oxygen Therapy in Neonates

By Wally Carlo MD, Maximo Vento MD PhD, in consultation with Consulting Editor, Dr. Lucky Jain

Drs. Maximo Vento and Waldemar Carlo have compiled a state-of-the-art issue of the Clinics in Perinatology, focusing on Perinatal Pharmacology. This collection of clinical review articles delves into the latest advancements in oxygen therapy for neonates, providing healthcare professionals with evidence-based recommendations to improve patient outcomes.

Monitoring and Assessment of Oxygenation in Infants

This article reviews the current methods and technologies used to monitor oxygenation levels in infants, highlighting the importance of accurate assessment for optimal care.

Oxygen Toxicity in Neonates

This piece explores the risks associated with oxygen toxicity in newborns, discussing preventive measures and treatment options for this potentially life-threatening condition.

New Methods for Non-Invasive Oxygen Administration

Discover the latest innovations in non-invasive oxygen delivery systems, designed to enhance patient comfort and reduce the risk of complications.

Targeting Oxygen in Preterm and Term Infants Starting at Birth

This article discusses the importance of targeted oxygen therapy from birth, outlining strategies for optimizing oxygen levels in both preterm and term infants.

Newborn Resuscitation in Settings Without Access to Supplemental Oxygen

Learn about the challenges and solutions for resuscitating newborns in resource-limited settings where supplemental oxygen may not be available.

Noninvasive Versus Invasive Ventilatory Support

This review compares the benefits and drawbacks of noninvasive and invasive ventilatory support methods, aiding healthcare providers in making informed decisions for their patients.

Nasal SIMV Versus Nasal CPAP Before and After Invasive Ventilatory Support

Examine the efficacy of nasal SIMV and nasal CPAP in both pre- and post-invasive ventilatory support scenarios, guiding practitioners in selecting the most appropriate treatment approach.

Is High-Flow Cannula Inferior to CPAP for Neonates?

This article addresses the ongoing debate regarding the comparative effectiveness of high-flow cannula versus CPAP for neonatal respiratory support.

Intermittent Hypoxia: Importance

Understand the significance of intermittent hypoxia in neonatal care, including its potential impact on long-term health outcomes.

Closed-Loop Control of Inspired Oxygen in Neonates: Compliance with Targets

Explore the role of closed-loop control systems in maintaining optimal oxygen levels, ensuring compliance with established targets and enhancing patient safety.

Meta-Analysis Oxygenation Saturation Targeting Trials: Do Infant Subgroups Matter?

This meta-analysis delves into the question of whether different infant subgroups respond differently to varying oxygen saturation targets, providing insights for personalized care.

Targets of Oxygen Saturation to Optimize Eye Outcomes

Learn about the specific oxygen saturation targets recommended to minimize the risk of retinopathy of prematurity and promote healthy eye development in preterm infants.

Achieved Oxygenation Saturations and Outcome in Extremely Preterm Infants

This study examines the relationship between achieved oxygenation saturations and health outcomes in extremely preterm infants, shedding light on the importance of precise oxygen management.

Pulmonary Hypertension in Preterm Infants

Understand the risks and management strategies for pulmonary hypertension in preterm infants, a critical aspect of neonatal care.

Current Recommendations and Practice of Oxygen Therapy in Preterm Infants

This concluding article summarizes the current evidence-based recommendations for oxygen therapy in preterm infants, serving as a valuable resource for healthcare providers seeking to deliver optimal care.