Genomes 5: A Comprehensive Textbook on Genomics and Genome Research

Written by Terry A. Brown, Genomes 5 is a thoroughly revised and updated edition of the popular textbook on genomics and genome research. This modern textbook provides a comprehensive overview of the latest techniques, tools, and applications in the field of genomics.

Organization and Coverage

The textbook is divided into four parts, covering techniques, genome anatomy, genome function, and genome evolution. The content spans the genomes of all types of organisms, including viruses, bacteria, fungi, plants, animals, and humans.

Techniques and Methods

The fifth edition includes comprehensive coverage of cutting-edge techniques, such as long-read DNA sequencing, genome-wide RNA mapping, CRISPR-Cas9, and GWAS methods for determining gene function. These techniques form the basis of the chapters that describe the three main types of genomes: eukaryotic, prokaryotic, and viral.

Genome Expression and Replication

The textbook provides an in-depth exploration of genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Additionally, it covers the applications of metabolomics and systems biology.

Genome Evolution

The final chapter delves into the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are also included, with explanations on why they remain important today.

Ideal for Upper-Level Courses

Genomes 5 is an ideal textbook for upper-level courses focused on genomics and genome research. Its highly accessible and well-structured content makes it easy for students to navigate and understand the complex concepts.

Key Features

• Superb artwork illustrates key concepts and mechanisms
• Each chapter includes short-answer questions and in-depth problems to test readers’ understanding
• Thoroughly up-to-date with references to the latest research from the 2020s

Publisher: CRC Press; 5th edition (March 21, 2023)
Language: English
Paperback: 560 pages
ISBN-10: 0367674076
ISBN-13: 978-0367674076