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Obesity and diabetes, two of the most pressing health concerns of the 21st century, are reaching epidemic proportions. The staggering cost of treating these conditions has sparked a pressing need for innovative and effective therapies. Fortunately, recent breakthroughs in incretin biology offer a beacon of hope in the fight against these debilitating diseases.
Incretins, a class of short peptide hormones, have been found to play a pivotal role in regulating glucose homeostasis, body weight, and food intake. Released from the gut in response to food transit, these hormones have been shown to have a profound impact on pancreatic function, as well as brain activity. As a result, incretin-based therapies have become a promising area of research, with numerous novel drugs being developed to tap into their potential.
This comprehensive guide provides an in-depth exploration of the rapidly evolving field of incretin biology. Following a historical perspective on the discovery of incretin therapies, the book delves into the clinical applications of these innovative treatments. Readers will gain insights into the cellular-level release of incretins from entero-endocrine cells, as well as their actions on the pancreas and brain.
The book also examines changes in incretins seen in diabetes and following bariatric surgery, providing valuable insights for researchers and clinicians alike. Furthermore, the potential side effects of incretin therapy are thoroughly discussed, ensuring that readers are well-equipped to navigate the complex landscape of this rapidly evolving field.
Each chapter is accompanied by a detailed methodology section, offering a practical guide to key techniques in incretin biology. This valuable resource spans the gamut from basic laboratory research to clinical practice, making it an indispensable tool for scientists, physicians, and bariatric surgeons.
ISBN-13: 9781783267361
Publisher: Imperial College Press
Publication Date: December 28, 2015
Pages: 216
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