Toxoplasma Gondii: A Comprehensive Guide to Parasite Biology and Disease

Written by leading specialists Erica S. Martins-duarte and Daniel Adesse, this book provides a thorough understanding of Toxoplasma gondii, a globally widespread protozoan parasite responsible for toxoplasmosis. With high seroprevalence rates in humans, particularly in South America, it’s essential to delve into the intricacies of this parasite.

Parasite Biology and Life Cycle

The book explores the life cycle of Toxoplasma gondii, including the ultrastructural features of tachyzoite and bradyzoite, as well as their main specific organelles. Readers will gain insight into the mechanisms of host cell invasion, parasite replication, and epigenetics regulation.

The authors also examine the mechanisms of pathogenesis and host immune response to Toxoplasma gondii infection, including purinergic signaling. Furthermore, they discuss the mechanisms of immune evasion employed by the parasite, providing a comprehensive understanding of the complex interactions between Toxoplasma gondii and its host.

The book covers relevant aspects of disease, including current chemotherapy options for toxoplasmosis and perspectives for future chronic disease treatment. Additionally, it explores epidemiology and methods for visualization of the parasite using optical and electron microscopy, making it an invaluable resource for researchers and healthcare professionals.

Language: English

ISBN-10: 1685072291

ISBN-13: 978-1685072292