Revolutionizing Cell Signaling: The Power of Non-Opsin-Based Optogenetics

Optogenetics represents a breakthrough technology capable of dynamically modulating molecular and cellular activity in live cells with high precision. This transformative technology has made it possible to reversibly interrogate protein actions, cellular events, and animal behaviors with a simple flash of light.

The Evolution of Optogenetics: From Opson-Based to Opson-Free

Manipulating the temporal and spatial profile of light has enabled precise control of membrane potentials, inspiring the development of non-opsin-based optogenetics. This opson-free approach not only inherits the precise spatiotemporal resolution but also expands the targets into a diverse pool of biomolecules such as membrane receptors, ion channels, kinases, GTPases, and transcription factors.

A Unique Focus on Opson-Free Optogenetic Tools

This book is unique in its emphasis on the design and applications of opson-free optogenetic tools. It introduces cutting-edge methods for precise modulation of cell signaling and highlights applications of optogenetic regulation of cellular functions.

What You’ll Learn

• New developments in non-opsin-based optogenetic tools
• Cutting-edge methods for precise modulation of cell signaling
• Applications of optogenetic regulation of cellular functions

Contributions from an international team of leading experts make this book an invaluable resource for researchers and scientists in the field.

Related Resources

For further reading, explore these related titles:

• Cell Signaling by W. Lim and B. Mayer
• Cancer Cell Signaling: Targeting Signaling Pathways Toward Therapeutic Approaches to Cancer edited by K. Ayyanathan
• Optical Probes in Biology edited by J. Zhang et al.

Product Details:

Publisher: CRC Press
1st Edition: December 14, 2022
Language: English
Hardcover: 186 pages
ISBN-10: 1032249226
ISBN-13: 978-1032249223