Unlocking the Power of Spinal Interneurons: A Comprehensive Guide

The spinal cord is a complex structure comprising four types of neurons: motor neurons, pre-ganglionic neurons, ascending projection neurons, and spinal interneurons. Among these, spinal interneurons have garnered significant attention due to their remarkable ability for neuroplasticity, adapting to persistent activity, neural injury, or disease.

The Role of Spinal Interneurons in Neural Circuits

Spinal interneurons process information within local circuits and possess the unique ability to sprout and rewire entire neural circuits, contributing to the restoration of disrupted neural communication after spinal cord injury. Their axons, although restricted to the same structure as the soma, can bypass the lesion site, facilitating recovery.

The classification, identification, and study of spinal interneurons are crucial in understanding their role in specific neural circuits and their neuroplasticity. By uncovering the capacity for neuroplasticity and identifying optimal spinal interneurons for recovery, researchers can pinpoint cellular candidates for developing innovative therapies.

A Comprehensive Reference Book for Neuroscientists, Clinicians, and Industry Professionals

“Spinal Interneurons” provides a focused overview of the techniques used to identify and study these cells, their roles in normal and compromised neural circuits, and the scientific evidence supporting their neuroplasticity. This reference book is an invaluable resource for neuroscientists, clinicians, and trainees seeking to understand the therapeutic potential of spinal interneurons.

Industry professionals will also benefit from this comprehensive guide, which compiles the latest in therapeutic strategies for targeting spinal interneurons, considers the development and use of treatments, and explores how existing treatments can be translated to the clinic and reverse-translated to the bench.

Product Details:

• Publisher: Academic Press

• Edition: 1st edition

• Publication Date: December 16, 2022

• Language: English

• Paperback: 474 pages

• ISBN-10: 0128192607

• ISBN-13: 978-0128192603