Cell Transplantation and Gene Therapy in Neurodegenerative Disease: Advances and Challenges

This groundbreaking volume, part of the International Review of Neurobiology series, presents cutting-edge advances in cell transplantation and gene therapy for neurodegenerative diseases. Edited by Emma Lane, Cheney Drew, and Mariah Lelos, this comprehensive release brings together international experts to share their insights on the latest developments and challenges in this rapidly evolving field.

Exploring the Challenges and Opportunities in Cell and Gene Therapy

The book delves into the complexities of translating cell therapies to Good Manufacturing Practice (GMP), the hurdles in developing cell therapies for Huntington’s disease, and the challenges of gene therapy in this debilitating condition. Additionally, it covers the technological advances and barriers to gene therapy, as well as the considerations for developing cell therapy modulation for spinal cord injury treatment.

New Perspectives on Cell and Gene Therapy for Neurodegenerative Diseases

Other chapters explore the role of cell and gene therapy in current animal models of Parkinson’s and Huntington’s disease, the potential of biomaterials to support cell therapy in degenerative disease, and the neurosurgical challenges and innovations in cell and gene therapy delivery. Neuroimaging is also discussed, highlighting the challenges of harnessing imaging tools to facilitate cell and gene therapy in neurodegenerative diseases.

Considerations for Clinical Trials and Patient Involvement

The book also examines the considerations for clinical trial design for novel advanced therapeutics in neurodegenerative disease, as well as the crucial role of patients in advanced therapy medicinal product (ATMP) development and trials for neurodegenerative disease.

Product Details:
Publisher: Academic Press
Publication Date: November 30, 2022
Language: English
Pages: 324
ISBN-10: 0323989373
ISBN-13: 978-0323989374