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Authored by Rita Ferreira, “Glycolysis: Tissue-Specific Metabolic Regulation in Physio-Pathological Conditions” is a groundbreaking book that delves into the intricacies of glycolysis, covering its biochemistry, physiology, and therapeutic applications. This exhaustive resource provides a multidisciplinary approach to understanding glycolytic events in both healthy biology and disease pathology.
The book commences with a thorough overview of fundamental glycobiology, followed by in-depth chapters on glycolysis physiology in various organs and systems. The author sheds light on the physiological significance of glycolysis in different tissues, highlighting its crucial role in maintaining cellular homeostasis.
The book also explores the complex relationship between glycolytic alterations and various disease conditions, including cancer, heart failure, diabetes, inborn glycolytic pathway defects, hematologic malignancies, osteoporosis, neurodegenerative diseases, and viral infections. This comprehensive coverage provides valuable insights into the pathophysiological aspects of glycolysis.
In addition to its role in disease pathology, the book examines glycolysis as a promising therapeutic target and its implications for drug discovery efforts. The author discusses the latest methodologies and approaches employed in this realm, illuminating the potential for glycolysis-based treatments.
To facilitate further research in this domain, the book provides step-by-step descriptions of experimental protocols, setup, and analysis. It covers cutting-edge techniques such as omics and computational modeling, interactive study methods, and glycolysis flux measurement. These detailed instructions enable researchers to explore new avenues in glycolysis research.
Featuring contributions from international leaders in the field, this book is an indispensable resource for scientists, researchers, and students seeking a thorough understanding of glycolysis and its far-reaching implications.
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