Nucleic Acids: A Novel Target for Metal Chelate-Based Drugs

The rising cost of treating human diseases, coupled with the growing resistance of disease-causing agents, has created a pressing need for innovative and effective drug molecules. Despite the abundance of drugs in the market, patients often face the daunting challenge of managing side effects that can compromise their immune system.

In this context, metal chelate-based drugs have emerged as a promising solution, offering a paradigm shift in drug design. As metal ions are integral components of biological molecules, they can be engineered to target specific molecules, including nucleic acids, while minimizing damage to healthy cells.

Unlocking the Potential of Metal Complexes

This book provides a comprehensive overview of recent advances in the design and development of metal-based molecules and their interactions with biomolecules, particularly nucleic acids. The authors delve into the structural elucidation of metal complexes using cutting-edge techniques and explore their binding patterns with specific targets.

The book addresses the challenges of developing new metal-based drugs, highlighting recent methods and approaches adopted to generate novel molecules. Furthermore, it examines the role of advanced optical techniques in characterizing metal-based drugs, offering insights into their potential applications.

Key Features

• Focuses on recent advances and methods in metal-based drug design
• Explores the interactions between metal complexes and biomolecules, including nucleic acids
• Addresses the challenges of developing new metal-based drugs
• Covers recent advances in optical techniques for characterizing metal-based drugs

Publisher: Elsevier Science
Publication Date: August 20, 2023
Language: English
ISBN: 9780128205037, 9780128205044