Biomechanics of Coronary Atherosclerotic Plaque: A Comprehensive Guide

By Jacques Ohayon, “Biomechanics of Coronary Atherosclerotic Plaque: From Model to Patient” is a groundbreaking text that delves into the biomechanical studies conducted over the past decade. These studies have significantly enhanced our understanding of coronary atherosclerotic plaque initiation, growth, and rupture. Moreover, they have improved the design of medical devices and clinical interventions, including surgical procedures.

This book serves as a valuable resource for students, researchers, engineers, clinicians, and interventional cardiologists. It provides an in-depth overview of the main topics related to the biomechanics of atherosclerosis in a single volume, penned by several experts in the field.

Part of the Biomechanics of Living Organs Book Series

The biomechanics of human soft tissues and organs has been an emerging research field since the publication of Y.C. Fung’s original book series in the 1990s. The publication of such books entirely dedicated to a specific biomechanical subject is necessary to advance scientific research in the field of biomechanics and to transfer important knowledge to future generations. Therefore, this series of volumes on the biomechanics of living organs has been created.

This series began in July 2017 with the publication of a first volume on the fundamentals of Hyperelastic Constitutive Laws for Finite Element Modeling of Living Organs. The current volume on the Biomechanics of Coronary Atherosclerotic Plaque, is the latest in this new series.

Key Features of the Book

The book presents the main computational fluid dynamic studies performed, describing blood flow in healthy and pathological artery branches, including in coronary bifurcations. It highlights the correlation between plaque initiation regions and blood shear stress amplitude. Moreover, it discusses the main biomechanical and mechanobiological models to highlight the importance of quantifying the residual and peak cap stresses and the presence of -calcifications to evaluate the risk of plaque rupture.

Furthermore, the book introduces the most recent intravascular imaging biomarker techniques (elastography, palpography, and modulography) to provide a comprehensive understanding of the biomechanics of coronary atherosclerotic plaque.

Author and Publication Details

Author: Jacques Ohayon

Publication Date: March 15, 2020

Language: English

ISBN: 9780323859332, 9780128171967