Process Chemistry in the Pharmaceutical Industry: A Comprehensive Guide

By Wenyi Zhao, the second edition of this book reflects the significant changes in process chemistry since the first edition. It includes more common process issues such as safety, cost, robustness, and environmental impact. Notable progress has been made in areas like process safety, stereochemistry, new reagents, and reagent surrogates.

Forty years ago, there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity, especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies.

Key Features

This unique volume, now in its second edition, is designed to provide readers with an unprecedented strategy and approach that will help chemists and graduate students develop chemical processes in an efficient manner. It promotes an industrial mindset concerning safety and commercial viability when developing methods. The author discusses development strategies with case studies and experimental procedures.

Focusing on mechanism-guided process development, this book provides readers with practical strategies and approaches. It addresses more common process issues such as safety, cost, robustness, and environmental impact.

Target Audience

This book provides a new direction for scientists, researchers, and students in materials science and polymer chemistry who seek to better understand the chemistry behind conducting polymers and improve their performance for use in advanced energy applications.

Published by CRC Press, this book is available in English and is a must-have for anyone looking to gain insights into the latest developments in process chemistry in the pharmaceutical industry.