Skin Science Contributions in Clinical Dermatology

Edited by Dr. John J. DiGiovanna, this issue of Dermatologic Clinics delves into the latest advancements in skin science and its impact on clinical dermatology. The comprehensive collection of articles covers a wide range of topics, including:

Mosaic mTORopathies

Exploring the genetic and molecular mechanisms underlying mosaic mTORopathies, this article provides insights into the diagnosis and treatment of these complex conditions.

CYLD: Cause and Therapeutic Target for Cylindromas

This piece discusses the role of CYLD in the development of cylindromas and its potential as a therapeutic target for the treatment of these benign skin tumors.

Current Status of Dedicator of Cytokinesis (DOCK), DOCK8, DOCK2

Delving into the functions and implications of DOCK proteins in human health, this article highlights their significance in immune system regulation and disease pathogenesis.

IL-22 relation to Tumor Aggression and Role of Cyclosporine

This article examines the relationship between IL-22 and tumor aggression, shedding light on the potential therapeutic applications of cyclosporine in cancer treatment.

Dual Lineage of Dermal Fibroblasts and Potential for Scar Correction, Reformation of Adnexal Structures

Investigating the dual lineage of dermal fibroblasts, this piece explores the potential for scar correction and the reformation of adnexal structures through innovative therapeutic approaches.

Inflammasome Instigated Autoinflammatory Disorders

Discussing the role of inflammasomes in the development of autoinflammatory disorders, this article outlines current understanding and future directions for treatment.

Pigment Cell Biology

This article delves into the biology of pigment cells, providing insights into their function, regulation, and implications for human health.

Antimicrobial Peptides

Highlighting the importance of antimicrobial peptides in human defense against pathogens, this piece explores their potential as therapeutic agents.

Choosing Friend or Foe? Commensal-specific tolerance

Examining the complex relationship between the human immune system and commensal organisms, this article discusses the mechanisms of commensal-specific tolerance and its implications for human health.

With contributions from leading experts in the field, this issue of Dermatologic Clinics offers a comprehensive overview of the latest research and advancements in skin science and clinical dermatology.