Forensic DNA Profiling: A Comprehensive Guide

By Scott Bader (Author), Allan Jamieson (Editor)

The increasingly complex world of DNA profiling necessitates a reliable source of information for those seeking to understand its intricacies. Combining material from the acclaimed Wiley Encyclopedia of Forensic Science with newly commissioned and updated content, the editors have utilized their extensive experience in criminal casework worldwide to compile an informative guide that will provide valuable insights and thought-provoking articles to anyone involved or interested in the use of DNA in forensic contexts.

Introduction to Forensic DNA Profiling and Genetics

Forensic DNA profiling is a crucial tool in the investigation and prosecution of crimes. It involves the analysis of DNA samples collected from crime scenes and comparing them with DNA samples from known individuals to establish a match. Forensic genetics, on the other hand, is the application of genetic principles to aid in the investigation of crimes. This guide provides comprehensive coverage of these topics, including the sources of DNA, validation, and accreditation processes.

Analysis and Interpretation of DNA Evidence

The analysis and interpretation of DNA evidence are critical steps in forensic DNA profiling. This section of the guide covers the extraction, quantification, amplification, and interpretation of electropherograms (epgs). It also discusses the challenges and limitations of DNA analysis, such as dealing with mixed DNA samples, low template DNA, and DNA transfer.

Evaluation of DNA Evidence

Once DNA evidence has been analyzed and interpreted, it must be evaluated to determine its relevance and significance in a criminal investigation. This section of the guide discusses the evaluation of DNA mixtures, low template DNA, and DNA transfer. It also covers the use of DNA databases, paternity and kinship testing, mitochondrial-DNA analysis, wildlife DNA analysis, single-nucleotide polymorphism (SNP) analysis, phenotyping, and familial searching.

Applications of Forensic DNA Profiling

Forensic DNA profiling has a wide range of applications in criminal investigations and legal proceedings. This section of the guide explores the use of DNA databases, paternity and kinship testing, mitochondrial-DNA analysis, wildlife DNA analysis, SNP analysis, phenotyping, and familial searching. It also discusses the ethical and legal implications of these applications.

Courtroom Presentation of DNA Evidence

The presentation of DNA evidence in court is a critical aspect of forensic DNA profiling. This section of the guide covers the preparation of DNA reports, discovery, cross-examination, and current controversies surrounding DNA evidence. It provides practical advice for scientists, lawyers, and other professionals involved in the legal system.

This comprehensive guide is intended to be an authoritative yet accessible resource for anyone interested in forensic DNA profiling. With contributions from leading experts in the field, it offers a valuable addition to the literature on forensic science and genetics.