Fast Dissolving/Disintegrating Dosage Forms: A Comprehensive Guide

Fast Dissolving/Disintegrating Dosage Forms (FDDFs) have been commercially available since the late 1990s. Initially introduced as orodispersible tablets, they have evolved to include orodispersible films, granules, pellets, and mini-tablets, catering to specific populations such as pediatrics, geriatrics, and psychiatric patients. These dosage forms enable quicker onset of action, immediate drug delivery, and sometimes offer bioavailability benefits due to buccal/sublingual absorption.

With time, FDDFs have advanced to deliver drugs in a sustained and controlled manner. Their current market and application are increasing in demands with advances in age-adapted dosage forms for different patients and changing regulatory requirements that warrant mandatory assessments of new drugs and drug products before commercial availability.

This book presents detailed information about FDDFs from their inception to recent developments. It covers the technical details of various FDDF manufacturing methods, formulation aspects, evaluation, and methods to conduct clinical studies. The authors also provide examples of marketed fast disintegrating/dissolving drug products in the US, Europe, Japan, and India.

This reference is ideal for pharmacology students at all levels seeking information about this specific form of drug delivery and formulation. It serves as a comprehensive guide for those interested in understanding the evolution, development, and future prospects of FDDFs in the pharmaceutical industry.

Product Details:

Pages: 904

Publisher: Bentham Science Publishers

Publication Date: May 21, 2017

Language: English

ISBN-13: 978-1681084602