Brain Embryology and the Causes of Congenital Malformations: A Comprehensive Guide

This issue of Neuroimaging Clinics of North America, edited by Drs. Thierry A.G.M. Huisman and Avner Meoded, delves into the intricate world of brain embryology and the causes of congenital malformations. The articles within this issue provide a comprehensive overview of the subject, covering topics such as:

1. Neuroimaging of Normal Brain Development

Understanding the normal development of the brain is crucial for identifying and understanding abnormalities. This article explores the various neuroimaging techniques used to visualize and analyze the developing brain.

2. Ultrasound and MRI of the Normal Fetal Brain

Imaging the fetal brain is essential for prenatal diagnostics and monitoring. This article discusses the role of ultrasound and MRI in assessing the normal fetal brain development and detecting potential abnormalities.

3. Spinal Dysraphia, Chiari 2 Malformation, Unified Theory, and Advances in Fetoscopic Repair

Spinal dysraphia and Chiari 2 malformation are common congenital abnormalities affecting the spine and brain. This article presents a unified theory on these conditions and discusses recent advances in fetoscopic repair techniques.

4. Posterior Fossa Malformations

Posterior fossa malformations encompass a range of abnormalities affecting the cerebellum, brainstem, and surrounding structures. This article provides an in-depth analysis of these conditions, including their causes, diagnosis, and treatment options.

5. Synopsis of Brain Embryology

This article offers a concise overview of brain embryology, covering the key stages and processes involved in the development of the nervous system.

6. Cerebral Dysplasia and Overgrowth Syndromes

Cerebral dysplasia and overgrowth syndromes are characterized by abnormal brain growth and development. This article examines the causes, diagnosis, and management of these conditions.

7. Disorders of Ventral Induction/Spectrum of Holoprosencephaly

Disorders of ventral induction, including holoprosencephaly, result from abnormalities in the formation of the ventral forebrain. This article delves into the causes, classification, and treatment options for these conditions.

8. Classification and Neurogenetics of Intracranial Vascular Anomalies

Intracranial vascular anomalies can have significant implications for brain function and development. This article discusses the classification, genetic basis, and clinical implications of these conditions.

9. DTI of Brain Malformations: Exploring the Internal Architecture

Diffusion tensor imaging (DTI) is a powerful tool for understanding the internal architecture of brain malformations. This article explores the applications and findings of DTI in this context.

10. Connectomics in Brain Malformations: How is the Malformed Brain Wired?

Connectomics aims to map the neural connections within the brain. This article discusses the application of connectomics in understanding brain malformations and their impact on neural connectivity.

11. Commissural Anomalies

Commissural anomalies affect the structures that connect the two hemispheres of the brain. This article examines the causes, diagnosis, and treatment options for these conditions.

This comprehensive guide provides a detailed understanding of brain embryology and the causes of congenital malformations, making it an essential resource for researchers, clinicians, and students in the field of neuroimaging and developmental neuroscience.