Coagulation and Hematology in Neurological Surgery: A Comprehensive Guide

Edited by esteemed professionals Dr. Shahid Nimjee and Dr. Russell Lonser, this issue of Neurosurgery Clinics delves into the intricate world of Coagulation and Hematology in Neurological Surgery. The publication is designed to provide a detailed understanding of various aspects related to coagulation and its implications in neurosurgical practices.

Topics Covered

• Biology of Coagulation and Coagulopathy: An in-depth exploration of the biological processes involved in coagulation and the pathophysiological states that can lead to coagulopathy.
• Evaluation of Coagulation in the Neurosurgery Patient: A comprehensive guide on how to evaluate coagulation status in patients undergoing neurosurgical procedures.
• Genetics of Hyper- and Hypo-Coagulable States: This section delves into the genetic aspects that influence coagulation, shedding light on hyper-coagulable and hypo-coagulable states.
• Anticoagulants: Pharmacokinetics, Mechanisms of Action, and Indications: A detailed analysis of anticoagulant drugs, including their pharmacokinetic properties, mechanisms of action, and clinical indications.
• Use of Antiplatelet Agents in the Neurosurgical Patient: Insights into the use of antiplatelet agents in neurosurgical settings, highlighting their benefits and potential risks.
• Common Conditions Requiring Long-Term Anticoagulation in the Neurosurgical Patient: An overview of conditions that necessitate long-term anticoagulation therapy in neurosurgical patients.
• Reversal of Systemic and Antiplatelet Anticoagulants: Strategies and protocols for reversing the effects of anticoagulants in emergency situations.
• Intraoperative Blood and Factor Replacement in Neurosurgery: Guidance on managing blood and factor replacement during neurosurgical procedures.
• Management of Intraoperative Coagulopathy: Expert advice on managing coagulopathy that arises during surgical interventions.
• Deep Vein Thrombosis Prophylaxis in the Neurosurgical Patient: Prevention strategies for deep vein thrombosis in neurosurgical patients.
• Postoperative Anticoagulation after Neurological Surgery: Postoperative anticoagulation management strategies to minimize complications.
• Management of Venous Sinus Thrombosis: Diagnostic and therapeutic approaches for managing venous sinus thrombosis.
• Management of Acute Ischemic Thrombosis: Comprehensive management of acute ischemic thrombosis, including pharmacological and interventional treatments.
• Management of Intracranial Hemorrhage in the Anticoagulated Patient: Expert guidance on managing intracranial hemorrhage in patients who are anticoagulated.

This publication serves as a valuable resource for neurosurgeons, hematologists, and healthcare professionals seeking to enhance their understanding of coagulation and hematology in neurological surgery. It provides evidence-based information to aid in making informed decisions regarding patient care and management.