Liver Pathology: A Comprehensive Guide

Edited by Dr. John Hart, this issue of Surgical Pathology Clinics delves into the intricacies of liver pathology, encompassing a wide range of topics including hereditary cholestatic disorders, autoimmunity in the liver, fibrolamellar carcinoma, and more.

Hereditary Cholestatic Disorders: This section explores the genetic disorders that affect bile metabolism and transport, leading to cholestasis and potential liver damage.

Autoimmunity in the Liver: An in-depth look at how the immune system can mistakenly attack the liver, causing conditions such as autoimmune hepatitis and primary biliary cirrhosis.

Fibrolamellar Carcinoma: A rare type of liver cancer that predominantly affects young adults, this section discusses its diagnosis, treatment, and prognosis.

Hepatocellular Adenoma: A benign tumor of the liver, this topic covers its causes, symptoms, and treatment options.

Infections/Granulomas in the Liver: This section addresses various infections and granulomas that can affect the liver, including their causes, symptoms, and treatments.

HCV and Direct Acting Antivirals: An exploration of hepatitis C virus (HCV) and the direct-acting antiviral medications used to treat it.

Lymphomas in the Liver: A discussion on the various types of lymphoma that can affect the liver, including their diagnosis and treatment.

Viral Hepatitis: This topic covers the different types of viral hepatitis, their causes, symptoms, and prevention methods.

NASH: Non-alcoholic steatohepatitis, a condition characterized by inflammation and scarring in the liver, is discussed in detail.

Drug-Induced Liver Injury: An examination of how certain medications can cause liver damage and the importance of monitoring liver function while on these drugs.

PBC and AIH: Primary biliary cirrhosis and autoimmune hepatitis are two conditions that result from the immune system attacking the liver. This section delves into their causes, symptoms, and treatments.

Liver Transplant: This topic covers the process and outcomes of liver transplantation, a life-saving procedure for those with end-stage liver disease.

Frozen Sections of the Liver: A technical discussion on the preparation and examination of frozen liver tissue for diagnostic purposes.

Hepatocellular Carcinoma: The most common type of liver cancer, this section explores its causes, symptoms, and treatment options.

Cholangiocarcinoma: A rare cancer that affects the bile ducts, this topic covers its diagnosis, treatment, and prognosis.

With contributions from leading experts in the field, this comprehensive guide provides a thorough understanding of liver pathology, making it an essential resource for pathologists, hepatologists, and researchers alike.