Advances in Immunology, Volume 147: A Comprehensive Review

Authored by renowned immunologist, Frederick W. Alt, Advances in Immunology, Volume 147, presents a plethora of current developments and comprehensive reviews in the field of immunology. This latest release in the esteemed series delves into the intricacies of various immunological processes, shedding light on the latest research and findings.

Key Topics Covered

This volume encompasses a wide range of topics, including:

1. Histone deacetylases as targets in autoimmune and autoinflammatory diseases, exploring the role of these enzymes in modulating immune responses and their potential as therapeutic targets.
2. The advancing area of the mechanisms involved in the evolution of HIV-1 neutralizing antibodies, detailing the complex processes by which the immune system generates broadly neutralizing antibodies against HIV.
3. T cells in latent viral infections, discussing the critical role of T cells in controlling viral replication and the implications for vaccine development.
4. Communications of dendritic cells with T cells and NK cells in cancerous tissues, highlighting the complex interplay between these immune cells in the context of cancer.
5. Mechanism and Regulation of Class Switch Recombination by IgH transcriptional Control Elements, providing insights into the molecular mechanisms governing antibody class switching.
6. IL-2 partial agonist, examining the therapeutic potential of these molecules in modulating immune responses.
7. Preserving Immune Homeostasis with A20, focusing on the role of this ubiquitin-modifying enzyme in maintaining immune balance.
8. The design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies, outlining approaches aimed at inducing protective immunity against HIV.

By presenting these cutting-edge topics, Advances in Immunology, Volume 147, serves as an indispensable resource for researchers, scientists, and students seeking to deepen their understanding of the complex and rapidly evolving field of immunology.