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Resistance to Anti-CD20 Antibodies and Approaches for Their Reversal is a groundbreaking book that delves into the intricacies of B cell depletion and the treatment of B cell proliferative disorders, including non-Hodgkin’s lymphoma and chronic lymphocytic leukemia. Written by renowned international experts, this book provides in-depth insights into the mechanisms of resistance to anti-CD20 antibodies and explores innovative approaches for their reversal.
In the past two decades, anti-CD20 antibodies have revolutionized the treatment of B cell malignancies. However, a significant challenge remains – some patients fail to respond to initial therapy or experience early relapse. This book addresses this critical issue, presenting new and existing avenues surrounding anti-CD20 antibodies and their potential to improve treatment outcomes.
Recent years have seen the development of several next-generation anti-CD20 therapies, but predicting and reversing resistance remains a complex task. This book thoroughly explores these areas, which hold the key to enhancing anti-CD20 therapies and improving patient outcomes.
This comprehensive book is a valuable resource for researchers, students, and members of the biomedical and medical fields. It presents cutting-edge research, critical analyses, in-depth literature reviews, and the latest clinical reports on anti-CD20 antibody treatment. The book also discusses recent developments in the use of anti-CD20 antibodies in cancer and non-cancer diseases, possible resistance mechanisms, and their reversals, as well as the exciting therapeutic opportunities offered by anti-CD20 antibodies in combination with chemotherapy or other treatment modalities.
To facilitate a deeper understanding of complex concepts, the book features a range of diagrams to visually illustrate key information and numerous tables to summarize important data.
Publication details: Publisher: Elsevier Science; Publication date: August 30, 2023; Language: English; ISBN: 9780443192005, 9780443192012
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