Unlock the Secrets of the Immunological Synapse: A Comprehensive Guide

Edited by renowned expert Clment Thomas, “The Immunological Synapse, Part A, Volume 173” in the esteemed Methods in Cell Biology series is a cutting-edge resource that provides researchers with state-of-the-art methods for studying the immunological synapse.

Explore Cutting-Edge Techniques and Methods

• Imaging polarized granule release at the cytotoxic T cell immunological synapse using TIRF microscopy: control by polarity regulators
• Analysis of centrosomal area actin reorganization and centrosome polarization upon lymphocyte activation at the immunological synapse
• P815-based redirected degranulation assay to study human NK cell effector functions
• Cytotoxic and Chemotactic Dynamics of Natural Killer Cells Quantified by Live-cell Imaging
• Quantification of interaction frequency between antigen-presenting cells and T cells by conjugation assay
• Study of the Effects of NK-Tumor Cell Interaction by Proteomic Analysis and Imaging
• Quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers
• An in vitro model to monitor natural killer cell effector functions against primary breast cancer
• Standardized Protocol for the Evaluation of Chimeric Antigen Receptor (CAR)-modified Cell Immunological Synapse Quality using the Glass-supported Planar

This comprehensive volume covers various methods related to the study of the immunological synapse, providing researchers with detailed, point-by-point methods, as well as important notes and insights from an international board of leading scientists.

With its authoritative and expert guidance, “The Immunological Synapse, Part A, Volume 173” is an essential resource for researchers, scientists, and students seeking to advance their understanding of the immunological synapse and its applications in immunology, cell biology, and cancer research.

Product Details:

• Publisher: Elsevier Science
• Publication Date: January 16, 2023
• Language: English
• ISBN: 9780323901543, 9780323901550