Unravel the Secrets of the Immunological Synapse with Methods in Cell Biology Series

Explore the cutting-edge techniques and methods for studying the immunological synapse with the latest addition to the esteemed Methods in Cell Biology series, Volume 173. This comprehensive volume, authored by Clment Thomas, delves into the intricacies of the immunological synapse, providing researchers with a wealth of knowledge and expertise to advance their research.

State-of-the-Art Methods for Immunological Synapse Research

The book covers a range of topics, including:

• Imaging polarized granule release at the cytotoxic T cell immunological synapse using TIRF microscopy: control by polarity regulators
• Analysis of centrosomal area actin reorganization and centrosome polarization upon lymphocyte activation at the immunological synapse
• P815-based redirected degranulation assay to study human NK cell effector functions
• Cytotoxic and Chemotactic Dynamics of Natural Killer Cells Quantified by Live-cell Imaging
• Quantification of interaction frequency between antigen-presenting cells and T cells by conjugation assay

These chapters provide in-depth, point-by-point methods, accompanied by important notes and insights from leading international scientists.