Understanding Hepatitis B Virus: Prevention, Care, and Treatment

By Tarek I. Hassanein MD, in collaboration with Consulting Editor, Dr. Norman Gitlin, this comprehensive guide on Hepatitis B Virus (HBV) provides the most current information on the prevention and care of infected patients. It is a valuable resource for healthcare professionals and researchers in the field of hepatology.

Global Perspective on HBV Infections in the Era of Effective Vaccines

This section offers insights into the global prevalence of HBV infections and the impact of effective vaccines on reducing the incidence of the disease. It highlights the importance of vaccination in preventing HBV infections and the role of public health initiatives in promoting vaccination.

Understanding the Natural History of HBV Infection and the New Definitions of Cure and the Endpoints of Clinical Trials

This article delves into the natural history of HBV infection, including the various stages of the disease and the new definitions of cure. It also discusses the endpoints of clinical trials, providing a framework for evaluating the efficacy of treatment options.

HBV/HCV Coinfection in the Era of HCV-DAAs

This section focuses on the coinfection of HBV and HCV, particularly in the context of the availability of direct-acting antivirals (DAAs) for HCV. It explores the challenges and opportunities in managing patients with coinfection and the implications for treatment strategies.

Antiretroviral Effects on HBV/HIV Coinfection and the Natural History of Liver Disease

This article examines the impact of antiretroviral therapy on HBV/HIV coinfection and the natural history of liver disease in these patients. It discusses the role of antiretroviral drugs in preventing liver disease progression and improving patient outcomes.

Impact of HBV Infection on HCC and Liver Transplantation

This section discusses the relationship between HBV infection and the development of hepatocellular carcinoma (HCC). It also explores the implications of HBV infection for liver transplantation, including the selection of suitable donors and the management of recipients.

HBV in Pregnant Women and Their Infants

This article addresses the issue of HBV infection in pregnant women and the risk of transmission to their infants. It outlines the preventive measures and treatment options available to reduce the risk of vertical transmission.

WHO Guidelines for Prevention, Care, and Treatment of Individuals Infected with HBV: A US Perspective

This section presents the World Health Organization’s guidelines for the prevention, care, and treatment of individuals infected with HBV, with a focus on the US perspective. It highlights the key recommendations and strategies for healthcare providers and public health officials.

Reconciling the Difference between the Major HBV Treatment Guidelines: AASLD, EASL, APASL

This article compares and contrasts the treatment guidelines for HBV infection from the American Association for the Study of Liver Diseases (AASLD), the European Association for the Study of the Liver (EASL), and the Asian Pacific Association for the Study of the Liver (APASL). It aims to reconcile the differences and provide a unified approach to managing HBV-infected patients.

HBV/HDV Coinfection: A Challenge for Therapeutics

This section discusses the challenges posed by coinfection with HBV and hepatitis delta virus (HDV). It explores the available treatment options and the need for further research to develop effective therapies for this complex condition.

The Effects of Hepatic Steatosis on the Natural History of HBV Infection

This article examines the impact of hepatic steatosis on the natural history of HBV infection. It discusses the role of steatosis in disease progression and the implications for treatment strategies.

This comprehensive guide provides healthcare professionals and researchers with the current information they need to manage patient outcomes effectively. It covers all aspects of HBV prevention, care, and treatment, making it an invaluable resource in the field of hepatology.