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Microbial biofilms are a significant concern in medical settings, associated with substantial mortality and morbidity rates. Infections related to biofilms not only prolong recovery times but also escalate the cost of disease management.
Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms, making them a formidable foe in the fight against infectious diseases. The close proximity of microbes within biofilms also promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and contributing to the growing prevalence of diseases associated with resistance.
Fortunately, rapid advances in science and technology have led to the development of innovative strategies to mitigate the impact of biofilms on human health. Recent research has shed light on new and emerging concepts in microbial biofilm research, including the mechanisms of biofilm formation, biofilm-induced pathogenesis, and detection and diagnosis methods.
The book, Microbial Biofilms: Role in Human Infectious Diseases, provides an in-depth exploration of the complex world of microbial biofilms. It delves into critical topics such as gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, including surface coating, signal quenching, and novel compounds that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.
This book fulfills the knowledge gap in biofilm study, providing concise, thorough, and up-to-date information about the crucial role of microbial biofilms in human diseases. With its focus on new and emerging concepts in microbial biofilm research, this book is an invaluable resource for researchers, scientists, and healthcare professionals seeking to understand and combat the threats posed by microbial biofilms.
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