Digital Molecular Biology, Second Edition: A Comprehensive Guide to Molecular Diagnostics

Written by renowned author Chang-Hui Shen, Digital Molecular Biology, Second Edition is a definitive guide to the principles and applications of molecular biology in the clinical laboratory. This comprehensive textbook provides a clear and concise explanation of molecular biology fundamentals, along with detailed procedures and explanations of commonly used techniques and instrumentation.

The Foundations of Molecular Biology

The book covers the essential principles of molecular biology, including:

• Nucleic acids: structure, function, and analysis
• Proteins: structure, function, and analysis
• Chromosomes: structure, function, and analysis

Molecular Diagnostic Techniques

The book provides in-depth coverage of molecular diagnostic techniques, including:

• Whole exome sequencing (WES)
• Whole genome sequencing (WGS)
• RNA-seq
• ChIP-seq
• Next-generation sequencing (NGS) applications
• Detection of respiratory virus infections, including influenza, RSV, hAdV, hRV, and COVID-19

Applying Molecular Biology in the Clinical Laboratory

The textbook places protocols into context with practical applications, covering topics such as:

• Using information technology to communicate and assess results in the lab
• The role of molecular biology in future precision medicine
• Clinical applications of molecular diagnostics

New Features and Updates

This fully updated second edition includes recent advances in molecular diagnostics, including:

• New chapters on respiratory viruses, including COVID-19
• Expanded coverage of NGS applications
• Enhanced discussion on the role of molecular biology in precision medicine

Digital Molecular Biology, Second Edition is an essential resource for students, researchers, and clinicians seeking to deepen their understanding of molecular biology and its applications in the clinical laboratory.

Publisher: Elsevier Science

Publication Date: June 29, 2023

Language: English

ISBN: 9780323917889, 9780323986090