Exocytosis and Membrane Trafficking: A Comprehensive Guide

Edited by Arun Anantharam and Jefferson Knight, this book is a authoritative resource for researchers and students seeking a broad understanding of exocytosis and membrane trafficking. The book is divided into three sections, providing a cohesive and comprehensive molecules-to-systems presentation of secretory pathways.

Section 1: Components of Exocytotic Pathways

The first section delves into the formation and packaging of secretory organelles, explaining the essential constituents for exocytosis. This section lays the foundation for understanding the complex processes of exocytosis and membrane trafficking.

Section 2: Biophysical Insights from Synthetic and Reconstituted Systems

The second section presents two chapters on recently published reconstituted systems of SNARE-mediated fusion, offering valuable biophysical insights into the mechanisms of exocytosis. Researchers will appreciate the detailed descriptions of methodologies routinely used by biophysicists, including electrochemistry, electrophysiology, reconstitution assays, and high-resolution fluorescence imaging.

Section 3: Physiological Systems of Exocytosis

The final section summarizes the cellular and molecular mechanisms of exocytosis and its regulation in diverse systems, including yeast exocytosis and exosomal secretion. This section provides a thorough understanding of the physiological aspects of exocytosis and its significance in various cell types.

Historical perspectives on exocytosis are also presented and discussed, adding depth and context to the topic. With contributions from highly regarded researchers in the field, this book is an invaluable resource for anyone seeking a comprehensive understanding of exocytosis and membrane trafficking.

Key Features:

• Comprehensive and cohesive molecules-to-systems presentation of key features of secretory pathways
• A single volume description of exocytosis regulatory mechanisms in many different cell types
• Contributions from highly regarded researchers in the field
• Detailed descriptions of diverse systems of exocytosis, including yeast exocytosis and exosomal secretion
• Incorporates methodologies that are routinely used by biophysicists to study exocytosis and membrane fusion

Product Details:

Publisher: Iop Publishing Ltd

Publication Date: February 28, 2023

Language: English

Hardcover: 200 pages

ISBN-10: 0750337699

ISBN-13: 978-0750337694